1999 RH253 = (720135)

This is a partial list of unnumbered minor planets for principal provisional designations assigned between 1 January and 15 September 1999. As of June 2024, a total of 400 bodies remain unnumbered for this period.Objects for this year are listed on the following pages: A–R · S–T and U–Y. Also see previous and next year.

#720135 Color Information

In a RGB color space, hex #720135 is composed of 44.7% red, 0.4% green and 20.8% blue. Whereas in a CMYK color space, it is composed of 0% cyan, 99.1% magenta, 53.5% yellow and 55.3% black. It has a hue angle of 332.4 degrees, a saturation of 98.3% and a lightness of 22.5%. #720135 color hex could be obtained by blending #e4026a with #000000. Closest websafe color is: #660033. color 720135


The hexadecimal color #720135 has RGB values of R:114, G:1, B:53 and CMYK values of C:0, M:0.99, Y:0.54, K:0.55. Its decimal value is 7471413.


Influenza A virus H1N1-derived circNP37 positively regulates viral replication by sponging host miR-361-5p

  • Chunyu Zhu, Jingyu Wang, Yalan Du, Chunli Li, Mengchan Hao, Yu Zhang, Xiaoqing Zhang, Yiwei Guan, Fangliang Zheng, Yuan Zhang, View ORCID ProfileJianjun Chen

doi: https://doi.org/10.1101/2023.09.04.556164

Summary

RNA viruses, such as respiratory syncytial virus and SARS-CoV-2, can generate viral circular RNAs (circRNAs), which may play important roles during viral infection. However, whether influenza A viruses have this ability to generate viral circRNAs remains unknown. In this study, we discovered that the negative-strand RNA of the H1N1 nucleoprotein (NP) gene can generate a circRNA, designated circNP37. Furthermore, we demonstrated that circNP37 positively regulated viral replication by competitively sponging host miR-361-5p which inhibited polymerase basic protein 2 (PB2) expression. These results were confirmed using in vivo experiments. Compared with wild-type virus, infection with circNP37 knockout virus resulted in a reduced viral load in the lungs. This study demonstrates, for the first time, the existence and biological function of H1N1-derived circNP37. These findings help us better understand the mechanisms of influenza virus replication and pathogenicity.

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¿Cuáles son los Múltiplos de 720135?

Los Múltiplos del número 720135 son los que te indicamos a continuación:

  • Múltiplos de 720135:

720135, 1440270, 2160405, 2880540, 3600675, 4320810, 5040945, 5761080, 6481215, 7201350, 7921485, 8641620, 9361755, 10081890, 10802025, 11522160, 12242295, 12962430, 13682565, 14402700, 15122835, 15842970, 16563105, 17283240, 18003375, 18723510, 19443645, 20163780, 20883915, 21604050, 22324185, 23044320, 23764455, 24484590, 25204725, 25924860, 26644995, 27365130, 28085265, 28805400, 29525535, 30245670, 30965805, 31685940, 32406075, 33126210, 33846345, 34566480, 35286615, 36006750

Debido a que los múltiplos de un número son infinitos, solo hemos colocado los primeros 50 múltiplos de 720135

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